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Chromosome 10 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 10 spans about 133 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells. Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 10 likely contains between 800 and 1,200 genes.〔(Chromosome 10 - Genetics Home Reference )〕 ==Genes== The following are some of the genes located on chromosome 10: * ALOX5: Arachidonate 5-Lipoxygenase (processes essential fatty acids to leukotrienes, which are important agents in the inflammatory response; also facilitates development and maintenance of cancer stem cells, slow-dividing cells thought to give rise to a variety of cancers, including leukemia); * CAMK1D: calcium/calmodulin-dependent protein kinase ID * CDH23: cadherin-like 23 * CXCL12: chemokine (C-X-C motif) ligand 12, SDF-1, ''scyb12'' * EGR2: early growth response 2 (Krox-20 homolog, Drosophila) * ERCC6: excision repair cross-complementing rodent repair deficiency, complementation group 6 * FGFR2: fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) * HELLS: Lymphoid-specific helicase * PCBD1: 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) * PCDH15: protocadherin 15 * PTEN gene: phosphatase and tensin homolog (mutated in multiple advanced cancers 1) * RET: ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) * UROS: uroporphyrinogen III synthase (congenital erythropoietic porphyria) * PROSER2: proline and serine rich 2 or c10orf47 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Chromosome 10 (human)」の詳細全文を読む スポンサード リンク
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